Detecting strategic disclosure shifts in US biopharma 10-K filings. MD&A narrative · Tone · Readability · Topic · Cosine similarity. Built as a portfolio demo on doctoral research examining how cyclical financial performance and top management team changes affect annual report language.
Pre-loaded companies · MDA section · Real 10-K filings
Pipeline shift from oncology to inflammation. Horizon Therapeutics acquisition (2023) created major disclosure expansion and a vocabulary break from prior years.
Aducanumab (Aduhelm) FDA approval in 2021 — the most contested drug approval in two decades. Disclosure language shifted dramatically around pipeline risk and regulatory strategy.
REGEN-COV antibody cocktail dominated 2020 MD&A. Post-COVID portfolio diversification — Eylea HD, Dupixent expansion — visible in 2022–23 disclosure evolution.
Research Context